There is no dog breed that is 100 percent hypoallergenic. It is not the pup's coat that causes the allergic reaction, but enzymes in its saliva that stick to its hair and skin after the pup has licked it. When the dead skin, or dander, is shed, everyone around the pup breathes it in. Breeds that shed less hair also shed less dander and generally are considered less of an allergy risk.
Hypoallergenic Dog Breeds
Poodles, and poodle hybrids, such as the labradoodle or cockapoo, come high up on the hypoallergenic breed list. Water dog breeds, such as the Spanish and Portuguese varieties, also shed less, likely one reason Bo Obama made it to the White House. Bichon frise, Maltese, schnauzers and several of the terrier breeds, including the Bedlington and Kerry blue make it onto the American Kennel Club list of low-shedding breeds. Almost hairless dog breeds, like the Chinese crested, are also listed.